Travel vaccination

Rabies Vaccination

The rabies vaccine provides pre-exposure protection against the rabies virus, which is almost always fatal once symptoms appear. A three-dose pre-exposure course is recommended for higher-risk travellers visiting areas where rabies is present.

£75 per dose

£90 per dose — 3 dose course

Who it is for

Higher-risk travellers to areas where rabies is present, including long-stay visitors, those in remote locations and people with greater animal contact.

Number of doses

Three doses for the pre-exposure course.

When to have it

Complete the course before travel; ideally start three to four weeks before departure.

How long protection lasts

A completed course provides long-lasting immune priming; a booster may be advised for those at continued risk.

How it is given

By injection into the upper arm.

Price

£75 per dose

Quick answer

The rabies vaccine is a three-dose pre-exposure course that protects higher-risk travellers against rabies, a virus that is almost always fatal once symptoms appear. It is recommended for those visiting rabies-affected areas of Asia, Africa and the Americas, especially on longer or remote trips. The pre-exposure rabies vaccine is available at Crewe Travel Clinic in Crewe, Cheshire.

About Rabies Vaccination

Rabies is a viral infection spread through the bite, scratch or lick of an infected animal, most commonly dogs but also bats, monkeys and other mammals. Once symptoms develop the disease is almost always fatal, so prevention and prompt treatment after any exposure are critical.

The virus is present in many parts of the world, particularly across Asia, Africa and parts of Central and South America. Travellers can reduce their risk by avoiding contact with animals, but vaccination provides valuable additional protection, especially where medical care may be difficult to reach quickly.

The pre-exposure rabies vaccine is given as a three-dose course before travel. Having it does not remove the need for treatment after a bite, but it simplifies the follow-up care required and provides an important head start. Your travel health nurse will assess your itinerary and activities to advise whether it is suitable for you.

Timing

Course completed before travel

The three doses are given over three to four weeks, so it is best to start the course in good time before departure; an accelerated schedule may be possible.

Effectiveness

High level of protection

Completing the pre-exposure course primes the immune system so that fewer follow-up doses and no rabies immunoglobulin are needed if you are later exposed.

Duration

Long-term priming

A completed pre-exposure course provides long-lasting immune priming, though prompt post-exposure treatment is still essential after any bite or scratch.

Signs & symptoms

  • Fever, headache and general weakness or tiredness in the early stages
  • Tingling, itching or pain around the site of the bite or scratch
  • Anxiety, confusion and agitation
  • Difficulty swallowing and fear of water (hydrophobia)
  • Excess saliva and muscle spasms
  • Progression to paralysis, coma and almost certain death once symptoms appear

Who should consider this vaccine?

Pre-exposure rabies vaccination may be advised for travellers to areas where rabies is present, particularly those staying for longer periods, travelling to remote locations, or undertaking activities with higher animal contact. It is especially worth considering for cyclists, runners, those working with animals and travellers far from reliable medical care. Your travel health nurse will assess your risk before recommending it.

High Risk Areas

Rabies occurs across much of Asia, Africa, and parts of Central and South America, with dog-mediated rabies a particular risk in many of these regions. Bat-related rabies is found in many areas worldwide, including parts of the Americas and Europe.

Traveller Risk Factors

Those most at risk include travellers to rabies-endemic areas with limited healthcare access, long-stay visitors and expatriates, those undertaking cycling, running or trekking, people working with or around animals, and children who may be more likely to approach animals.

Who should have this vaccine

Pre-exposure rabies vaccination may be advised for travellers to countries where rabies is present, particularly where access to prompt medical care and rabies treatment may be limited. Your travel health nurse will assess your destination, length of stay and planned activities before recommending the course.

  • Travellers to rabies-endemic areas of Asia, Africa and parts of the Americas
  • Long-stay visitors, expatriates and those travelling to remote locations
  • Cyclists, runners, trekkers and those undertaking outdoor activities
  • People working with or around animals, including bats
  • Young children, who may be more likely to approach animals and not report a bite

The vaccination course

The pre-exposure course is given as three separate doses by injection into the upper arm, usually over three to four weeks. It is best to start in good time so the course is finished before departure, although an accelerated schedule may be possible for travellers who are short of time.

  • Three doses given on days 0, 7 and 21 to 28
  • An accelerated schedule may be available where time is limited
  • Best started well before departure to allow the course to be completed
  • Suitable from a young age following an individual risk assessment

How long does protection last

A completed pre-exposure course primes the immune system for the long term. It does not remove the need for treatment after a bite or scratch, but it simplifies follow-up care, reduces the number of doses needed afterwards and means rabies immunoglobulin is not required. A booster may be advised for those at ongoing or repeated risk.

  • Provides long-lasting immune priming after the full course
  • Prompt post-exposure treatment is still essential after any bite, scratch or lick
  • Fewer follow-up doses and no immunoglobulin needed if previously vaccinated
  • A booster may be considered for those with continued exposure risk

Possible side effects

The rabies vaccine is generally well tolerated and most side effects are mild and short-lived. Serious reactions are uncommon. If you have any concerns after vaccination, you can speak to our team or contact your GP or NHS 111.

  • Soreness, redness or swelling at the injection site
  • Headache and feeling generally unwell
  • Mild fever and muscle or joint aches
  • Tiredness, which usually settles within a day or two

Frequently asked questions

Medically reviewed by Crewe Travel Clinic clinical team · Last reviewed 13 June 2026

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