Yellow Fever Vaccination & Certificate — Crewe Travel Clinic

Yellow Fever Vaccination & Certificate

Everything you need to know about yellow fever, the Stamaril vaccine and the International Certificate of Vaccination or Prophylaxis (ICVP) — now valid for life — at our registered Yellow Fever Vaccination Centre.

In short

Yellow fever is a serious mosquito-borne viral disease found in parts of sub-Saharan Africa and tropical South America, and many countries require proof of vaccination for entry. The Stamaril vaccine is given as a single dose, and only a registered Yellow Fever Vaccination Centre can issue the official International Certificate of Vaccination or Prophylaxis (ICVP), which is now valid for life. Crewe Travel Clinic is a registered Yellow Fever Vaccination Centre serving travellers across Crewe, Nantwich, Stoke-on-Trent and the wider Cheshire area.

What it protects against

Yellow fever, a serious mosquito-borne viral infection found in parts of sub-Saharan Africa and tropical Central and South America.

Vaccine used

Stamaril, a single-dose live vaccine, suitable from 9 months of age following an individual assessment.

Certificate (ICVP)

The International Certificate of Vaccination or Prophylaxis is now valid for life and becomes valid 10 days after vaccination.

Where it can be given

Only at a registered Yellow Fever Vaccination Centre, which alone can issue a valid ICVP — Crewe Travel Clinic is one such centre.

When to have it

At least 10 days before travel, so the certificate is valid before you arrive at your destination.

Exemptions

Travellers for whom the vaccine is unsuitable may be issued a medical waiver letter after assessment, where appropriate.

What is yellow fever and why it matters for travellers

Yellow fever is a viral infection spread by mosquitoes that bite during the day. The illness can begin with a sudden fever, headache and muscle aches, and while many people recover, a proportion go on to develop a severe phase with jaundice, bleeding and organ failure that can be fatal. There is no specific treatment, so prevention through mosquito-bite avoidance and vaccination is essential. The disease is found in tropical regions of sub-Saharan Africa and Central and South America, and the risk to an individual traveller depends on the destination, the time of year and the activities planned.

  • Spread by daytime-biting mosquitoes in affected regions
  • Can cause fever, jaundice, bleeding and organ failure in severe cases
  • No specific cure, so prevention is the priority
  • Risk varies by country, season and itinerary

The Stamaril vaccine

Stamaril is the yellow fever vaccine used in the UK. It is a live vaccine given as a single injection, usually into the upper arm, and provides strong, long-lasting protection in the large majority of people who receive it. A single dose is now considered to give life-long immunity for most travellers, in line with WHO and TravelHealthPro guidance. Because it is a live vaccine, a careful assessment of your age, health, allergies and itinerary is needed before vaccination — this is why it can only be given at a registered centre by trained staff. The dose should be given at least 10 days before travel, as the certificate only becomes valid after this period.

  • Single-dose live vaccine, suitable from 9 months of age after assessment
  • Provides life-long protection for most people
  • Given at least 10 days before departure
  • Requires an individual suitability assessment before vaccination

The ICVP certificate — now valid for life

Proof of yellow fever vaccination is recorded on the International Certificate of Vaccination or Prophylaxis (ICVP), a yellow document recognised under the International Health Regulations. Since 2016, a single dose is accepted as giving lifelong protection, and the ICVP is now valid for the life of the person vaccinated — earlier certificates that stated a 10-year validity remain valid for life and do not need renewing. The certificate only becomes valid 10 days after the date of vaccination, so booking in good time is important. To be valid, the ICVP must be completed correctly and bear the official stamp of a registered Yellow Fever Vaccination Centre; a vaccine given elsewhere without this stamp will not be accepted at borders.

  • Recognised internationally under the International Health Regulations
  • Now valid for life — older 10-year certificates also remain valid for life
  • Becomes valid 10 days after vaccination
  • Only valid when stamped by a registered Yellow Fever Vaccination Centre
  • Keep it with your passport and carry it whenever you travel

Who needs yellow fever vaccination and a certificate

There are two separate reasons a traveller may need yellow fever vaccination: to protect their own health where the disease is present, and to meet a country's entry requirements. Some countries require proof of vaccination from all arriving travellers, while others require it only from those arriving from, or transiting through, a country with a risk of yellow fever transmission. Requirements can differ even for short stopovers, so it is essential to check the rules for every country on your itinerary. You can use our yellow fever certificate checker to look up requirements by country before you book.

  • Recommended for health protection where yellow fever is present
  • Required for entry to some countries as a condition of arrival
  • May be required if arriving from or transiting an affected country
  • Check requirements for every destination and stopover, not just the main one
  • Use our certificate checker to confirm what your trip requires

Exemptions and medical waivers

The yellow fever vaccine is not suitable for everyone. It may be unsuitable for infants under 9 months, people with weakened immune systems, those with a serious allergy to a vaccine component such as egg, and some older travellers, depending on the individual assessment. Where a traveller has a genuine medical reason not to be vaccinated but is travelling to a country that requires proof, a registered centre may issue a medical waiver (exemption) letter on the official certificate after a careful assessment. A waiver is not a guarantee of entry — the final decision rests with the destination country — so reducing mosquito-bite risk and discussing the itinerary in detail are especially important for these travellers.

  • May be unsuitable for infants under 9 months and some older adults
  • Not generally given to people with significantly weakened immunity
  • Avoided in those with a serious allergy to a vaccine component
  • A medical waiver letter may be issued after assessment where appropriate
  • A waiver does not guarantee entry; the destination country decides

A registered Yellow Fever Vaccination Centre near you

Crewe Travel Clinic is a registered Yellow Fever Vaccination Centre, which means we are authorised to administer Stamaril and to issue the official ICVP certificate. We see travellers from across Crewe, Nantwich, Sandbach, Alsager and Stoke-on-Trent, as well as the wider Cheshire and Staffordshire area. At your appointment, a travel health professional will review your itinerary, age and health, confirm whether the vaccine is suitable for you, check the entry requirements for each country on your trip, and complete your certificate correctly. Because the certificate only becomes valid 10 days after vaccination, we recommend booking well ahead of departure.

  • Authorised to vaccinate and to issue the official ICVP certificate
  • Serving Crewe, Nantwich, Stoke-on-Trent and the wider Cheshire area
  • Full itinerary and suitability assessment at every appointment
  • Book early so your certificate is valid before you travel

Related travel vaccines

Related diseases

Malaria

Malaria is a serious and sometimes fatal disease caused by Plasmodium parasites, spread to people through the bites of infected female Anopheles mosquitoes in tropical and subtropical regions. There is no vaccine for travellers, so prevention relies on antimalarial tablets and mosquito bite avoidance.

Typhoid Fever

Typhoid fever is a serious bacterial infection caught from food and water contaminated with the bacterium Salmonella Typhi. It is a risk in areas with poor sanitation, particularly the Indian subcontinent, and travellers prevent it through scrupulous food and water hygiene combined with typhoid vaccination.

Hepatitis A

Hepatitis A is a viral infection of the liver spread through contaminated food and water and poor sanitation. Travellers prevent it through good food and water hygiene combined with a highly effective vaccine, which gives long-lasting protection.

Rabies

Rabies is a viral infection of the nervous system, spread through the saliva of infected animals, most often by a bite, scratch or lick on broken skin. It is found across Asia, Africa and parts of the Americas, and is almost always fatal once symptoms appear. Travellers reduce their risk by avoiding contact with animals, knowing what to do after any exposure, and, where appropriate, having pre-travel rabies vaccination at Crewe Travel Clinic.

Dengue Fever

Dengue fever is a viral infection spread by daytime-biting Aedes mosquitoes across the tropics and subtropics. Most travellers prevent it through diligent mosquito-bite avoidance, with a vaccine available for selected travellers who have had dengue before.

Zika Virus

Zika virus is a mosquito-borne infection that is usually mild but can cause serious birth defects if a woman is infected during pregnancy. There is no vaccine, so prevention relies on mosquito-bite avoidance, careful pregnancy and travel planning, and avoiding sexual transmission.

Frequently asked questions

Medically reviewed by Crewe Travel Clinic clinical team · Last reviewed 13 June 2026

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