Travel vaccination

Yellow Fever Vaccination (Stamaril)

Stamaril protects against yellow fever, a serious mosquito-borne viral infection found in parts of Africa and South America. It is given as a single dose at an approved Yellow Fever Vaccination Centre, with an international certificate provided.

£75 per dose

£75 per dose — single-dose course

Who it is for

Travellers aged 9 months and over visiting areas of sub-Saharan Africa or Central and South America where yellow fever occurs, or where proof of vaccination is required for entry.

Number of doses

A single dose, now considered to provide life-long protection for most people.

When to have it

At least 10 days before travel, as the international certificate becomes valid 10 days after vaccination.

How long protection lasts

Life-long for most people, with the international certificate valid for life.

How it is given

A single injection, usually into the upper arm, at an approved Yellow Fever Vaccination Centre.

Price

£75 per dose

Quick answer

Stamaril is a single-dose vaccine that protects against yellow fever, a serious mosquito-borne disease found in parts of Africa and South America. It must be given at an approved Yellow Fever Vaccination Centre, which issues an international certificate (ICVP) valid for life from ten days after vaccination, and some countries require proof of vaccination for entry. The yellow fever vaccine is available at Crewe Travel Clinic, an approved centre in Crewe, Cheshire.

About Yellow Fever Vaccination (Stamaril)

Yellow fever is a viral infection spread by mosquitoes that bite during the day. It can cause fever, jaundice, bleeding and organ failure, and severe cases can be fatal. There is no specific treatment, so vaccination is the most effective form of protection.

The disease is found in tropical regions of sub-Saharan Africa and Central and South America. Many of these countries require proof of vaccination for entry, and some neighbouring countries require it for travellers arriving from affected areas, so checking entry requirements is essential.

Stamaril must be given at an approved Yellow Fever Vaccination Centre, which can issue an International Certificate of Vaccination or Prophylaxis (ICVP). Crewe Travel Clinic provides this service. Your travel health nurse will assess your itinerary, age and health to advise whether the vaccine is suitable for you.

Timing

At least 10 days before travel

The single dose should be given at least ten days before travel, as the international certificate becomes valid ten days after vaccination.

Effectiveness

Very high level of protection

A single dose provides strong, long-lasting protection against yellow fever in the large majority of people who receive it.

Duration

Life-long

A single dose is now considered to provide life-long protection for most people, and the international certificate is valid for life, although some travellers may be advised to have a booster in specific circumstances.

Signs & symptoms

  • Sudden high fever and chills
  • Headache and muscle or back pain
  • Nausea, vomiting and loss of appetite
  • Jaundice (yellowing of the skin and eyes)
  • Bleeding from the mouth, nose or eyes in severe cases
  • Organ failure, which can be fatal without treatment

Who should consider this vaccine?

Yellow fever vaccination may be advised for travellers visiting areas where the disease is present, and is required for entry to some countries. It is often mandatory for travellers moving between affected regions. Vaccination must be given at an approved centre, which issues the international certificate; your travel health nurse will check the requirements for your itinerary and confirm whether the vaccine is suitable for you.

High Risk Areas

Yellow fever occurs in tropical regions of sub-Saharan Africa and Central and South America. Many of these countries either have a risk of yellow fever or require proof of vaccination for entry, particularly for travellers arriving from other affected areas.

Traveller Risk Factors

Those most at risk include travellers to affected areas of Africa and South America, those visiting rural or forested regions, long-stay visitors, and anyone travelling between countries with entry requirements. Some travellers, including older adults and those with certain health conditions, may need additional assessment before vaccination.

Who should have this vaccine

Yellow fever vaccination may be advised for travellers aged 9 months and over who are visiting areas of sub-Saharan Africa or Central and South America where the disease occurs. It is also required for entry to a number of countries, and may be required for travellers arriving from other affected regions. Stamaril is a live vaccine, so a careful assessment of your age, health and itinerary is needed to confirm it is suitable for you.

  • Travellers to affected areas of Africa and South America
  • Those visiting rural, forested or jungle areas, or staying for longer periods
  • Travellers needing a certificate to satisfy country entry requirements
  • People moving between countries with yellow fever entry rules
  • Not suitable for some groups, including those with weakened immunity, certain allergies, or infants under 9 months without specialist advice

The vaccination course

A single dose of Stamaril provides protection for most people and is now considered to give life-long immunity. The dose should be given at least 10 days before travel, because the International Certificate of Vaccination or Prophylaxis (ICVP) only becomes valid 10 days after vaccination. Stamaril must be given at an approved Yellow Fever Vaccination Centre, which can issue the official certificate.

  • One injection, usually into the upper arm
  • Should be given at least 10 days before departure
  • ICVP certificate issued at the time of vaccination
  • Booking in good time ensures the certificate is valid before you travel

How long does protection last

A single dose is now considered to provide life-long protection for most people, and the international certificate is valid for life. In line with WHO and TravelHealthPro guidance, a booster dose is no longer routinely required. However, some travellers may be advised to have an additional dose in specific circumstances, which your travel health nurse will discuss with you.

  • Strong, long-lasting protection from a single dose
  • International certificate valid for life
  • A booster may be advised for certain travellers, such as those vaccinated when very young, during pregnancy, or with weakened immunity
  • Your nurse will check whether a further dose is appropriate for your circumstances

Possible side effects

Most people have only mild, short-lived side effects after the yellow fever vaccine. Because Stamaril is a live vaccine, your travel health nurse will assess your suitability carefully before vaccinating, particularly for older adults and people with certain health conditions. Serious reactions are very rare.

  • Soreness, redness or swelling at the injection site
  • Headache, mild fever and tiredness
  • Muscle aches
  • Symptoms usually settle within a few days
  • Seek medical advice if you feel seriously unwell in the days after vaccination

Frequently asked questions

Medically reviewed by Crewe Travel Clinic clinical team · Last reviewed 13 June 2026

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