Travel vaccination

Tick-Borne Encephalitis Vaccination

The tick-borne encephalitis (TBE) vaccine protects against a viral infection of the brain and nervous system spread by the bites of infected ticks. It may be advised for travellers visiting forested and rural areas of Europe and Asia.

£70 per dose

£70 per dose — 3 dose course

Who it is for

Travellers visiting forested or rural areas of Europe and Asia, particularly those hiking, camping or working outdoors in spring and summer.

Number of doses

Three doses for the standard primary course, with accelerated schedules available for those travelling sooner.

When to have it

Ideally several weeks before travel, so at least two doses can be given before departure.

How long protection lasts

Several years after the primary course, with boosters advised for continued exposure.

How it is given

By injection into the upper arm muscle.

Price

£70 per dose

Quick answer

The tick-borne encephalitis (TBE) vaccine protects against a tick-borne viral infection of the brain and nervous system. It is given as a three-dose course and may be advised for travellers visiting forested or rural parts of Europe and Asia, especially those hiking or camping in spring and summer. The TBE vaccine is available at Crewe Travel Clinic in Crewe, Cheshire.

About Tick-Borne Encephalitis Vaccination

Tick-borne encephalitis is a viral infection passed to humans through the bite of an infected tick, and occasionally through unpasteurised milk or dairy products from infected animals. Many people have no symptoms or only a mild, flu-like illness, but in some cases the virus goes on to affect the brain and central nervous system, which can lead to serious and sometimes long-lasting complications.

The ticks that carry the virus live in woodland, grassland and forested areas, and are most active during the spring and summer months. Travellers who walk, hike, camp or work in these environments are at greater risk of being bitten.

The TBE vaccine is given as a course of three doses and helps the body build protection against the virus. Your travel health nurse will assess your destination, planned activities and the time of year to advise whether vaccination is suitable for you.

Timing

Start several weeks before travel

The course is ideally started well in advance, as two doses are usually needed before travel to provide initial protection, with the schedule sometimes accelerated for those leaving sooner.

Effectiveness

High level of protection

Completing the full course produces a strong protective immune response against tick-borne encephalitis in the large majority of people.

Duration

Several years with boosters

After the primary course, a booster is usually advised within a few years and at intervals thereafter to maintain protection for those with continued exposure.

Signs & symptoms

  • Fever and a flu-like illness in the first phase
  • Headache, tiredness and aching muscles
  • Nausea and loss of appetite
  • A second phase affecting the brain, with severe headache and a high temperature
  • Stiff neck, confusion or drowsiness
  • In severe cases, seizures, paralysis or long-lasting neurological problems

Who should consider this vaccine?

Vaccination may be advised for travellers visiting forested or rural parts of Europe and Asia, particularly those planning outdoor activities such as hiking, camping or fieldwork. It is especially worth considering during the spring and summer tick season. Your travel health nurse will assess your itinerary and activities before recommending it.

High Risk Areas

Tick-borne encephalitis is found in forested and rural areas across central, eastern and northern Europe, including parts of Austria, Germany, Switzerland, the Baltic states and Scandinavia, as well as Russia and parts of central and eastern Asia, including northern China and Japan.

Traveller Risk Factors

Those most at risk include travellers who walk, hike, camp, cycle or work outdoors in affected forested or rural areas, particularly during the spring and summer months when ticks are most active. Longer stays and frequent outdoor exposure further increase the risk.

Who should have this vaccine

Tick-borne encephalitis vaccination may be advised for travellers visiting forested, grassland or rural areas of central, eastern and northern Europe and parts of Asia where the virus circulates. The risk is highest for those spending time outdoors during the spring and summer tick season. A travel health assessment considers your destination, planned activities and time of year before vaccination is recommended.

  • Travellers hiking, camping, cycling or walking in affected rural and forested areas
  • People working outdoors, such as in forestry, farming or fieldwork
  • Those staying for longer periods or making repeated visits to risk areas
  • Trips planned during the peak tick season from spring to autumn

The vaccination course

The TBE vaccine is given as a primary course of three doses into the upper arm muscle. The first two doses build initial protection, and the third dose extends longer-term immunity. The course should ideally be started several weeks before travel so that at least two doses are received beforehand. An accelerated schedule may be possible for those travelling at shorter notice.

  • Standard course is three doses
  • The first two doses provide initial protection before travel
  • Accelerated schedules are available when time is short
  • Suitable from one year of age, using an age-appropriate preparation

How long does protection last

Completing the full three-dose course produces a strong protective immune response against tick-borne encephalitis in the large majority of people. Protection lasts for several years, after which a booster dose is usually advised to maintain immunity for those with continued exposure to risk areas.

  • A high level of protection follows the completed course
  • The first booster is usually advised within a few years
  • Further boosters are given at intervals for ongoing exposure
  • Vaccination does not replace measures to avoid tick bites

Possible side effects

Most side effects of the TBE vaccine are mild and settle within a day or two. Serious reactions are uncommon. Your travel health nurse will discuss your medical history and any individual considerations before vaccination, and will advise you on what to expect afterwards.

  • Tenderness, redness or swelling at the injection site
  • Headache and tiredness
  • Muscle aches or a mild raised temperature
  • These effects are usually short-lived and resolve on their own

Frequently asked questions

Medically reviewed by Crewe Travel Clinic clinical team · Last reviewed 13 June 2026

Explore more